Primary hyperparathyroidism - related osteitis fibrosa cystica: Exceptional finding nowadays

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Osteitis fibrosa cystica—a forgotten radiological feature of primary hyperparathyroidism

Although bone disease and stone disease are the universally accepted classical manifestations of primary hyperparathyroidism, clinical parathyroid bone disease is rarely seen today in the United States (<5% of patients) and Western Europe. Nevertheless, in a given patient, classical skeletal involvement can be the first sign of primary hyperparathyroidism, but not recognized because it is not u...

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Spontaneous healing of osteitis fibrosa cystica in primary hyperparathyroidism.

A 24-year-old man with primary hyperparathyroidism and osteitis fibrosa cystica developed acute hypocalcaemia. Spontaneous healing of his bone disease was confirmed radiographically and by correction of the serum alkaline phosphatase. Hypercalcaemia associated with a raised serum parathyroid hormone recurred 90 weeks after the initial presentation. During the fourth neck exploration a parathyro...

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Successful Treatment of Osteitis Fibrosa Cystica from Primary Hyperparathyroidism

Osteitis Fibrosa Cystica (OFC) is defined as the classic skeletal manifestation of advanced primary hyperparathyroidism. With the increased detection by means of routine calcium screening, the clinical profile of primary hyperparathyroidism in Western countries has shifted from symptomatic disease to one with subtle or no specific symptoms ("asymptomatic" primary hyperparathyroidism). The autho...

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Normacalcaemic primary hyperparathyroidism with osteitis fibrosa.

THE diagnosis of primary hyperparathyroidism has been classically based upon the demonstration of high plasma calcium and low plasma phosphorus concentrations and an excessive urinary excretion of calcium. In recent years, however, it has become recognized that patients with primary hyperparathyroidism may present with plasma calcium concentrations that are within the normal range (George et al...

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Bisphosphonates can reduce bone hunger after parathyroidectomy in patients with primary hyperparathyroidism and osteitis fibrosa cystica.

OBJECTIVE To assess the effect of bisphosphonates on post-parathyroidectomy hypocalcemia in patients with osteitis fibrosa cystica. METHODS Review of the medical records of six patients using bisphosphonates preoperatively. RESULTS Mean age was 35.6 ± 10.5 years; serum calcium = 13.51 + 0.87 mg/dL; iPTH = 1,389 + 609 pg/mL. The mean value of urine deoxypyridinoline (UDPD) of three patients ...

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ژورنال

عنوان ژورنال: Bone Reports

سال: 2020

ISSN: 2352-1872

DOI: 10.1016/j.bonr.2020.100619